Influenza is a viral infection that attacks your respiratory system — your nose, throat and lungs. Influenza is commonly called the flu, but it's not the same as stomach "flu" viruses that cause diarrhea and vomiting.

For most people, influenza resolves on its own. But sometimes, influenza and its complications can be deadly. People at higher risk of developing flu complications include:

  • Young children under age 5, and especially those under 12 months
  • Adults older than age 65
  • Residents of nursing homes and other long-term care facilities
  • Pregnant women and women up to two weeks postpartum
  • People with weakened immune systems
  • People who have chronic illnesses, such as asthma, heart disease, kidney disease, liver disease and diabetes
  • People who are very obese, with a body mass index (BMI) of 40 or higher

Though the annual influenza vaccine isn't 100 percent effective, it's still your best defense against the flu.

Products & Services


Initially, the flu may seem like a common cold with a runny nose, sneezing and sore throat. But colds usually develop slowly, whereas the flu tends to come on suddenly. And although a cold can be a nuisance, you usually feel much worse with the flu.

Common signs and symptoms of the flu include:

  • Fever over 100.4 F (38 C)
  • Aching muscles
  • Chills and sweats
  • Headache
  • Dry, persistent cough
  • Fatigue and weakness
  • Nasal congestion
  • Sore throat

When to see a doctor

Most people who get the flu can treat themselves at home and often don't need to see a doctor.

If you have flu symptoms and are at risk of complications, see your doctor right away. Taking antiviral drugs may reduce the length of your illness and help prevent more-serious problems.

More Information


Flu viruses travel through the air in droplets when someone with the infection coughs, sneezes or talks. You can inhale the droplets directly, or you can pick up the germs from an object — such as a telephone or computer keyboard — and then transfer them to your eyes, nose or mouth.

People with the virus are likely contagious from the day or so before symptoms first appear until about five days after symptoms begin. Children and people with weakened immune systems may be contagious for a slightly longer time.

Influenza viruses are constantly changing, with new strains appearing regularly. If you've had influenza in the past, your body has already made antibodies to fight that particular strain of the virus. If future influenza viruses are similar to those you've encountered before, either by having the disease or by getting vaccinated, those antibodies may prevent infection or lessen its severity.

But antibodies against flu viruses you've encountered in the past can't protect you from new influenza strains that can be very different immunologically from what you had before.

Risk factors

Factors that may increase your risk of developing influenza or its complications include:

  • Age. Seasonal influenza tends to target children younger than 12 months of age and adults 65 years old or older.
  • Living or working conditions. People who live or work in facilities with many other residents, such as nursing homes or military barracks, are more likely to develop influenza. People who are hospitalized are also at higher risk.
  • Weakened immune system. Cancer treatments, anti-rejection drugs, long-term use of steroids, organ transplant, blood cancer or HIV/AIDS can weaken your immune system. This can make it easier for you to catch influenza and may also increase your risk of developing complications.
  • Chronic illnesses. Chronic conditions, including lung diseases such as asthma, diabetes, heart disease, neurological or neurodevelopmental disease, an airway abnormality, and kidney, liver or blood disease, may increase your risk of influenza complications.
  • Aspirin use under age 19. People who are younger than 19 years of age and receiving long-term aspirin therapy are at risk of developing Reye's syndrome if infected with influenza.
  • Pregnancy. Pregnant women are more likely to develop influenza complications, particularly in the second and third trimesters. Women who are up to two weeks postpartum also are more likely to develop influenza-related complications.
  • Obesity. People with a body mass index (BMI) of 40 or more have an increased risk of complications from the flu.


If you're young and healthy, seasonal influenza usually isn't serious. Although you may feel miserable while you have it, the flu usually goes away in a week or two with no lasting effects. But children and adults at high risk may develop complications such as:

  • Pneumonia
  • Bronchitis
  • Asthma flare-ups
  • Heart problems
  • Ear infections

Pneumonia is the most serious complication. For older adults and people with a chronic illness, pneumonia can be deadly.


The Centers for Disease Control and Prevention (CDC) recommends annual flu vaccination for everyone age 6 months or older.

Each year's seasonal flu vaccine contains protection from the three or four influenza viruses that are expected to be the most common during that year's flu season. This year, the vaccine will be available as an injection and as a nasal spray.

In recent years, there was concern that the nasal spray vaccine wasn't effective enough against certain types of flu. However, the nasal spray vaccine is expected to be effective in the 2019-2020 season. The nasal spray still isn't recommended for some groups, such as pregnant women, children between 2 and 4 years old with asthma or wheezing, and people who have compromised immune systems.

Most types of flu vaccines contain a small amount of egg protein. If you have a mild egg allergy — you get hives only from eating eggs, for example — you can receive the flu shot without any additional precautions. If you have a severe egg allergy, you should be vaccinated in a medical setting and be supervised by a doctor who is able to recognize and manage severe allergic conditions.

Mayo medical institution Minute: Why you need your flu shot now

Vivien Williams: Seasonal flu is a virus that attacks your respiratory system. Most people get better on their own, but, for some, the flu can be serious.

Tina Ardon, M.D.: Our babies, our younger children and our older adults definitely can get more sick from the flu. Patients who are already sick with other chronic conditions, are undergoing chemotherapy are more likely to have complications from the flu as well.

Vivien Williams: Complications include bronchitis, pneumonia and even heart problems.

Dr. Ardon: The vaccine for influenza is one our best defenses we have.

Vivien Williams: Dr. Tina Ardon says some people don't get the flu vaccine because they think it could cause the flu.

Dr. Ardon: The flu vaccine is what we call a dead vaccine. So you cannot get the actual flu from the flu vaccine.

Vivien Williams: You can't get the flu from a flu shot. FluMist, while safe for most people, contains a weakened form of the virus, so people with certain conditions should get a shot instead.

Dr. Ardon: Everyone who can get it should get it.

Vivien Williams: It takes two weeks for the vaccine to work, so get your flu shot now. For the Mayo medical institution News Network, I'm Vivien Williams.

Mayo medical institution Minute: The facts about three flu vaccine myths

Ian Roth: Influenza myth No. 1: The flu is like a cold. It will make you feel awful, but it isn't really harmful. Fact.

Gregory Poland, M.D.: Well, in the U.S. alone, last year 80,000 Americans died from influenza and its complications, and almost a million were hospitalized.

Ian Roth: The complications are the really dangerous part. Dr. Gregory Poland says influenza commonly leads to deadly pneumonia, meningitis, heart attacks, and complications for people with diabetes.

Ian Roth: Myth No. 2: I always get the flu from the flu shot. Fact.

Dr. Poland: It is impossible to get influenza from the vaccine.

Ian Roth: Dr. Poland says it's not uncommon for people to coincidentally get an upper respiratory infection in the weeks after getting a flu shot and assume it's connected. But he says studies have proven your odds of getting that minor upper respiratory infection from other viruses are identical whether you get the flu shot or not, so you might as well protect yourself from the more serious influenza.

Ian Roth: And myth No. 3: Science still doesn't know enough about vaccines to know if they're safe. Fact.

Ian Roth: Dr. Poland says vaccines are among the safest and most studied areas of modern medicine. In fact, it takes more study and research to get a vaccine approved than it does for an over-the-counter headache medicine like acetaminophen or ibuprofen. For the Mayo clinic News Network, I'm Ian Roth.

Controlling the spread of infection

The influenza vaccine isn't 100 percent effective, so it's also important to take measures such as these to reduce the spread of infection:

  • Wash your hands. Thorough and frequent hand-washing is an effective way to prevent many common infections. Or use alcohol-based hand sanitizers if soap and water aren't readily available.
  • Contain your coughs and sneezes. Cover your mouth and nose when you sneeze or cough. To avoid contaminating your hands, cough or sneeze into a tissue or into the inner crook of your elbow.
  • Avoid crowds. The flu spreads easily wherever people congregate — in child care centers, schools, office buildings, auditoriums and public transportation. By avoiding crowds during peak flu season, you reduce your chances of infection. And if you're sick, stay home for at least 24 hours after your fever subsides so that you lessen your chance of infecting others.

Oct. 04, 2019
  1. Jameson JL, et al., eds. Influenza. In: Harrison's Principles of Internal Medicine. 20th ed. New York, N.Y.: The McGraw-Hill Companies; 2018. https://accessmedicine.mhmedical.com. Accessed July 13, 2018.
  2. Zachary KC. Treatment of seasonal influenza in adults. https://www.uptodate.com/contents/search. Accessed July 13, 2018.
  3. Goldman L, et al., eds. Influenza. In: Goldman-Cecil Medicine. 25th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com. Accessed July 13, 2018.
  4. Bope ET, et al. The infectious diseases. In: Conn's Current Therapy 2018. Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. Accessed July 13, 2018.
  5. Live attenuated influenza vaccine [LAIV] (The nasal spray flu vaccine). Centers for Disease Control and Prevention. https://www.cdc.gov/flu/about/qa/nasalspray.htm. Accessed July 13, 2018.
  6. The flu: What to do if you get sick. Centers for Disease Control and Prevention. https://www.cdc.gov/flu/takingcare.htm. Accessed July 13, 2018.
  7. AskMayoExpert. Influenza vaccination. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.
  8. Grohskopf LA, et al. Prevention and control of seasonal influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2018-2019 influenza season. MMWR Recommendations and Reports. 2018;67:3.
  9. AskMayoExpert. Influenza. Mayo medical institution; 2017.
  10. Grohskopf LA, et al. Prevention and control of seasonal influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2019-2020 influenza season. MMWR Recommendations and Reports. 2019; doi: 10.15585/mmwr.rr6803a1.
  11. Tosh PK (expert opinion). Mayo medical institution. Sept. 4, 2019.


News from Mayo medical institution

Products & Services